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Last updated: 2016/11/27

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EGFR/CEN7q FISH Probe

  • Catalog # : FG0193
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  • Specification
  • Product Description:
  • Labeled FISH probes for identification of gene amplification using Fluoresecent In Situ Hybridization Technique.
  • Quality Control Testing:
  • Representative image of human diffuse large B-cell lymphoma stain with the dual color FISH probe.

  • Storage Instruction:
  • Store at 4°C in the dark.
  • Probe 1:
        Size:
        Fluorophore:
        Location:
  • EGFR
    Approximately 250 kb
    Texas Red
    7p11.2
  • Probe 2:
        Size:
        Fluorophore:
        Location:
  • CEN7q
    Approximately 460 kb
    FITC
    7q21
  • Probe Gap:
  • The gap between two probes is approximately 23,600 kb
  • Origin:
  • Human
  • Source:
  • Genomic DNA
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • DNA Hybridization
  • DNA Hybridization enlargeenlarge this image
  • Human lung adenocarcinoma(FFPE) stained with EGFR/CEN7q FISH Probe. Human lung adenocarcinoma showed EGFR amplification.
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 1956
  • Gene Name:
  • EGFR
  • Gene Alias:
  • ERBB,ERBB1,HER1,PIG61,mENA
  • Gene Description:
  • epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
  • Gene Summary:
  • The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq
  • Other Designations:
  • avian erythroblastic leukemia viral (v-erb-b) oncogene homolog,cell growth inhibiting protein 40,cell proliferation-inducing protein 61,epidermal growth factor receptor
  • Interactome
  • Interactome
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