AFF1/CEN4p FISH Probe
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Specification
Product Description
Labeled FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. (Technology).
Probe 1
Name: AFF1
Size: Approximately 450kb
Fluorophore: Texas Red
Location: 4q21Probe 2
Name: CEN4p
Size: Approximately 560kb
Fluorophore: FITC
Location: 4p13Origin
Human
Source
Genomic DNA
Reactivity
Human
Form
Liquid
Notice
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
Regulation Status
For research use only (RUO)
Quality Control Testing
Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
Supplied Product
DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe
Storage Instruction
Store at 4°C in the dark.
Note
Hybridization position of the probes on the chromosome:
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Applications
Fluorescent In Situ Hybridization (Cell)
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Gene Info — AFF1
Entrez GeneID
4299Gene Name
AFF1
Gene Alias
AF-4, AF4, AF4-MLL, MGC134969, MLL/AF4, MLLT2, PBM1
Gene Description
AF4/FMR2 family, member 1
Omim ID
159557Gene Ontology
HyperlinkGene Summary
DISCONTINUED: The record for PBM1 has been withdrawn by HGNC.
Other Designations
AF4-MLL fusion protein|MLL-AF4 fusion protein|MLL/AF4 fusion protein|myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 2|myeloid/lymphoid or mixed-lineage leukemia trithorax homolog 2|pre-B-cell monocytic leukemi
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Interactome
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Disease
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