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Last updated: 2017/7/23

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PLS3/CENXp FISH Probe

  • Catalog # : FG0164
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  • Specification
  • Product Description:
  • Labeled FISH probes for identification of gene amplification using Fluoresecent In Situ Hybridization Technique.
  • Storage Instruction:
  • Store at 4°C in the dark.
  • Note:
  • Hybridization position of the probes on the chromosome.

  • Probe 1:
        Size:
        Fluorophore:
        Location:
  • PLS3
    Approximately 170 kb
    Texas Red
    Xq23
  • Probe 2:
        Size:
        Fluorophore:
        Location:
  • CENXp
    Approximately 400 kb
    FITC
    Xp11.22
  • Probe Gap:
  • The gap between two probes is approximately 5,790 kb
  • Origin:
  • Human
  • Source:
  • Genomic DNA
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • DNA Hybridization
  • DNA Hybridization enlargeenlarge this image
  • Human Lung adenocarcinoma cells stained with PLS3/CENXp FISH Probe shows the PLS3 copy number gain.
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 5358
  • Gene Name:
  • PLS3
  • Gene Alias:
  • T-plastin
  • Gene Description:
  • plastin 3 (T isoform)
  • Gene Summary:
  • Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
  • Other Designations:
  • T isoform,T plastin,plastin 3
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