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Last updated: 2016/10/16

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  • Catalog # : FG0156
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  • Specification
  • Product Description:
  • Labeled FISH probes for identification of gene amplification using Fluoresecent In Situ Hybridization Technique. (Technology)
  • Form:
  • Liquid
  • Quality Control Testing:
  • Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.

    QC Testing of FG0156
  • Supplied Product:
  • DAPI Counterstain (1500 ng/mL ) 250 uL
  • Storage Instruction:
  • Store at 4°C in the dark.
  • Note:
  • Hybridization position of the probes on the chromosome.

  • Probe 1:
  • CDKN2C
    Approximately 150kb
    Texas Red
  • Probe 2:
  • CEN1q
    Approximately 600kb
  • Probe Gap:
  • The gap between two probes is approximately 102,000 kb
  • Origin:
  • Human
  • Source:
  • Genomic DNA
  • Notice:
  • We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Application Image
  • Fluorescent In Situ Hybridization (Cell)
  • Gene Information
  • Entrez GeneID:
  • 1031
  • Gene Name:
  • CDKN2C
  • Gene Alias:
  • INK4C,p18,p18-INK4C
  • Gene Description:
  • cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
  • Gene Summary:
  • The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq
  • Other Designations:
  • CDK6 inhibitor p18,OTTHUMP00000009730,OTTHUMP00000009731,OTTHUMP00000046546,cyclin-dependent inhibitor,cyclin-dependent kinase 4 inhibitor C,cyclin-dependent kinase 6 inhibitor p18,cyclin-dependent kinase inhibitor 2C
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