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ABCC1/CEN16q FISH Probe

  • Catalog # : FG0141
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Labeled FISH probes for identification of gene amplification using Fluoresecent In Situ Hybridization Technique. (Technology)
  • Form:
  • Liquid
  • Quality Control Testing:
  • Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.

    QC Testing of FG0141
  • Supplied Product:
  • DAPI Counterstain (1500 ng/mL ) 250 uL
  • Storage Instruction:
  • Store at 4°C in the dark.
  • Note:
  • Hybridization position of the probes on the chromosome.

  • Probe 1:
        Size:
        Fluorophore:
        Location:
  • ABCC1
    Approximately 410kb
    Texas Red
    16q21
  • Probe 2:
        Size:
        Fluorophore:
        Location:
  • CEN16q
    Approximately 700kb
    FITC
    16q12.1
  • Probe Gap:
  • The gap between two probes is approximately 32,500 kb
  • Origin:
  • Human
  • Source:
  • Genomic DNA
  • Notice:
  • We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Application Image
  • Fluorescent In Situ Hybridization (Cell)
  • Gene Information
  • Entrez GeneID:
  • 4363
  • Gene Name:
  • ABCC1
  • Gene Alias:
  • ABC29,ABCC,DKFZp686N04233,DKFZp781G125,GS-X,MRP,MRP1
  • Gene Description:
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • Gene Summary:
  • The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms. [provided by RefSeq
  • Other Designations:
  • ATP-binding cassette, sub-family C, member 1,LTC4 transporter,OTTHUMP00000045904,leukotriene C(4) transporter,multidrug resistance protein,multiple drug resistance protein 1,multiple drug resistance-associated protein
  • Gene Pathway
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