LAPTM4B/CEN8q FISH Probe
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More Files
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Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
human breast cancer (FFPE) stained with LAPTM4B/CEN8q FISH Probe . human breast cancer showed no LAPTM4B amplification.
Hybridization position of the probes on the chromosome.
Hybridization position of the probes on the chromosome.
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Specification
Product Description
Labeled FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. (Technology).
Probe 1
Name: LAPTM4B
Size: Approximately 300kb
Fluorophore: Texas Red
Location: 8q22.1Probe 2
Name: CEN8q
Size: Approximately 520kb
Fluorophore: FITC
Location: 8q11.21Probe Gap
The gap between two probes is approximately 48,900 kb.
Origin
Human
Source
Genomic DNA
Reactivity
Human
Form
Liquid
Notice
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
Regulation Status
For research use only (RUO)
Quality Control Testing
Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
Supplied Product
DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe
Storage Instruction
Store at 4°C in the dark.
Note
Hybridization position of the probes on the chromosome.
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Applications
Fluorescent In Situ Hybridization (Cell)
Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
human breast cancer (FFPE) stained with LAPTM4B/CEN8q FISH Probe . human breast cancer showed no LAPTM4B amplification. -
Gene Info — LAPTM4B
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Interactome
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Pathway
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Disease
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Publication Reference
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LAPTM4B gene copy number gain is associated with inferior response to anthracycline-based chemotherapy in hormone receptor negative breast carcinomas.
Rusz O, Papp O, Vízkeleti L, Molnár BÁ, Bende KC, Lotz G, Ács B, Kahán Z, Székely T, Báthori Á, Szundi C, Kulka J, Szállási Z, Tőkés AM.
Cancer Chemotherapy and Pharmacology 2018 May; [Epub].
Application：FISH, Human, Breast carcinomas.
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Abstracts : 29th European Congress of Pathology.
[No authors listed].
Virchows Archiv : an International Journal of Pathology 2017 Aug; 471(Suppl 1):1.
Application：FISH, Human, Human breast cancer.
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LAPTM4B gene copy number gain is associated with inferior response to anthracycline-based chemotherapy in hormone receptor negative breast carcinomas.
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