HOXA9/CEN7p FISH Probe
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Specification
Product Description
Labeled FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. (Technology).
Probe 1
Name: HOXA9
Size: Approximately 190kb
Fluorophore: Texas Red
Location: 7p15.2Probe 2
Name: CEN7p
Size: Approximately 700kb
Fluorophore: FITC
Location: 7p12.1Probe Gap
The gap between two probes is approximately 23,200 kb
Origin
Human
Source
Genomic DNA
Reactivity
Human
Form
Liquid
Notice
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
Regulation Status
For research use only (RUO)
Quality Control Testing
Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
Supplied Product
DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe
Storage Instruction
Store at 4°C in the dark.
Note
Hybridization position of the probes on the chromosome.
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Applications
Fluorescent In Situ Hybridization (Cell)
Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Human cervix cancer (FFPE) stained with HOXA9/CEN7p FISH Probe. Human cervix cancer showed no HOXA9 amplification. -
Gene Info — HOXA9
Entrez GeneID
3205Gene Name
HOXA9
Gene Alias
ABD-B, HOX1, HOX1.7, HOX1G, MGC1934
Gene Description
homeobox A9
Omim ID
142956Gene Ontology
HyperlinkGene Summary
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is highly similar to the abdominal-B (Abd-B) gene of Drosophila. A specific translocation event which causes a fusion between this gene and the NUP98 gene has been associated with myeloid leukemogenesis. [provided by RefSeq
Other Designations
homeo box A9|homeobox protein HOXA9|homeodomain protein HOXA9
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