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Last updated: 2016/12/4

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MYCN (Orange) FISH ProbeGMP

  • Catalog # : FG0100
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  • Specification
  • Product Description:
  • Labeled FISH probes for identification of gene amplification using Fluoresecent In Situ Hybridization Technique.
  • Quality Control Testing:
  • Representative images of neuroblastoma patient tissue stain with the FISH probe. The left image is two signals of MYCN gene (Orange) in a normal cell; the right image is higher copy number of MYCN gene (amplification) without chromosome enumeration probe.

    QC Testing of FG0100
  • Storage Instruction:
  • Store at -20°C in the dark.
  • Note:
  • Hybridization position of the probes on the chromosome.

  • Probe 1:
        Size:
        Fluorophore:
        Location:
  • MYCN
    Approximately 168kb
    Orange
    2p24.1
  • Origin:
  • Human
  • Source:
  • Genomic DNA
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Application Image
  • Fluorescent In Situ Hybridization
  • Gene Information
  • Entrez GeneID:
  • 4613
  • Gene Name:
  • MYCN
  • Gene Alias:
  • MODED,N-myc,NMYC,ODED,bHLHe37
  • Gene Description:
  • v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
  • Gene Summary:
  • This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. [provided by RefSeq
  • Other Designations:
  • N-myc proto-oncogene protein,neuroblastoma MYC oncogene,neuroblastoma-derived v-myc avian myelocytomatosis viral related oncogene,oncogene NMYC,pp65/67,v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived,v-myc myelocytomatosis viral
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