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BAP1/CEN3q FISH Probe

  • Catalog # : FG0092
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Labeled FISH probes for identification of gene amplification using Fluoresecent In Situ Hybridization Technique. (Technology)
  • Quality Control Testing:
  • Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.

    QC Testing of FG0092
  • Supplied Product:
  • DAPI Counterstain (1500 ng/mL ) 250 uL
  • Storage Instruction:
  • Store at 4°C in the dark.
  • Note:
  • Hybridization position of the probes on the chromosome:

  • Probe 1:
        Size:
        Fluorophore:
        Location:
  • BAP1
    Approximately 150kb
    TexRed
    3p21.1
  • Probe 2:
        Size:
        Fluorophore:
        Location:
  • CEN3q
    Approximately 500kb
    FITC
    3q12.1
  • Probe Gap:
  • The gap between two probes is approximately 43080 kb.
  • Origin:
  • Human
  • Source:
  • Genomic DNA
  • Notice:
  • We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
  • Regulation Status:
  • For research use only (RUO)
  • Publication Reference
  • Applications
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections) enlargeenlarge this image
  • Human lung adenocarcinoma (FFPE) stained with BAP1/CEN3q FISH Probe. Human lung adenocarcinoma showed no BAP1 gene amplification.
  • PDF DownloadProtocol Download
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections) enlargeenlarge this image
  • Human prostate cancer (FFPE) stained with BAP1/CEN3q FISH Probe. Human prostate cancer showed BAP1 gene amplification.
  • PDF DownloadProtocol Download
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections) enlargeenlarge this image
  • Human pancreatic cancer (FFPE) stained with BAP1/CEN3q FISH Probe. Human pancreatic cancer showed no BAP1 gene amplification.
  • PDF DownloadProtocol Download
  • Application Image
  • Fluorescent In Situ Hybridization (Cell)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 8314
  • Gene Name:
  • BAP1
  • Gene Alias:
  • DKFZp686N04275,FLJ35406,FLJ37180,HUCEP-13,KIAA0272,UCHL2,hucep-6
  • Gene Description:
  • BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
  • Gene Summary:
  • The protein encoded by this gene localizes to the nucleus and it interacts with the RING finger domain of the breast cancer 1, early onset protein (BRCA1). This gene is thought to be a tumor suppressor gene that functions in the BRCA1 growth control pathway. There are multiple polyadenylation sites found in this gene. [provided by RefSeq
  • Other Designations:
  • BRCA1 associated protein-1,cerebral protein-13,cerebral protein-6,ubiquitin carboxy-terminal hydrolase
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