LAMP2/CENXp FISH Probe
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Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Human colon cancer (FFPE) stained with LAMP2/CENXp FISH Probe. Human colon cancer showed no LAMP2 gene amplification
Hybridization position of the probes on the chromosome:
Hybridization position of the probes on the chromosome:
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Specification
Product Description
Labeled FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. (Technology).
Probe 1
Name: LAMP2
Size: Approximately 250kb
Fluorophore: Texas Red
Location: Xq24Probe 2
Name: CENXp
Size: Approximately 550kb
Fluorophore: FITC
Location: Xp11.22Probe Gap
The gap between two probes is approximately 70,000 kb.
Origin
Human
Source
Genomic DNA
Reactivity
Human
Form
Liquid
Notice
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
Regulation Status
For research use only (RUO)
Quality Control Testing
Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
Supplied Product
DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe
Storage Instruction
Store at 4°C in the dark.
Note
Hybridization position of the probes on the chromosome:
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Applications
Fluorescent In Situ Hybridization (Cell)
Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Human colon cancer (FFPE) stained with LAMP2/CENXp FISH Probe. Human colon cancer showed no LAMP2 gene amplification -
Gene Info — LAMP2
Entrez GeneID
3920Gene Name
LAMP2
Gene Alias
CD107b, LAMPB, LGP110
Gene Description
lysosomal-associated membrane protein 2
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins. [provided by RefSeq
Other Designations
OTTHUMP00000023943|OTTHUMP00000023944|lysosome-associated membrane protein 2
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