MYCN/CEN2p FISH Probe
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Hybridization position of the probes on the chromosome.
Hybridization position of the probes on the chromosome.
-
Specification
Product Description
Labeled FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. (Technology).
Probe 1
Name: MYCN
Size: Approximately 270kb
Fluorophore: Texas Red
Location: 2p24.1Probe 2
Name: CEN2p
Size: Approximately 670kb
Fluorophore: FITC
Location: 2p11.2Probe Gap
The gap between two probes is approximately 69,000 kb
Origin
Human
Source
Genomic DNA
Reactivity
Human
Form
Liquid
Notice
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
Regulation Status
For research use only (RUO)
Quality Control Testing
Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
Supplied Product
DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe
Storage Instruction
Store at 4°C in the dark.
Note
Hybridization position of the probes on the chromosome. -
Applications
Fluorescent In Situ Hybridization (Cell)
-
Gene Info — MYCN
Entrez GeneID
4613Gene Name
MYCN
Gene Alias
MODED, N-myc, NMYC, ODED, bHLHe37
Gene Description
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
Gene Ontology
HyperlinkGene Summary
This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. [provided by RefSeq
Other Designations
N-myc proto-oncogene protein|neuroblastoma MYC oncogene|neuroblastoma-derived v-myc avian myelocytomatosis viral related oncogene|oncogene NMYC|pp65/67|v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived|v-myc myelocytomatosis viral
-
Interactome
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com