DTNB/CEN2p FISH Probe
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Human breast cancer (FFPE) stained with DTNB/CEN2p FISH Probe. Human breast cancer showed DTNB gene amplification
Hybridization position of the probes on the chromosome.
Hybridization position of the probes on the chromosome.
-
Specification
Product Description
Labeled FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. (Technology).
Probe 1
Name: DTNB
Size: Approximately 380kb
Fluorophore: Texas Red
Location: 2p24Probe 2
Name: CEN2p
Size: Approximately 670kb
Fluorophore: FITC
Location: 2p11.2Probe Gap
The gap between two probes is approximately 59,300 kb
Origin
Human
Source
Genomic DNA
Reactivity
Human
Form
Liquid
Notice
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
Regulation Status
For research use only (RUO)
Quality Control Testing
Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
Supplied Product
DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe
Storage Instruction
Store at 4°C in the dark.
Note
Hybridization position of the probes on the chromosome. -
Applications
Fluorescent In Situ Hybridization (Cell)
Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Human breast cancer (FFPE) stained with DTNB/CEN2p FISH Probe. Human breast cancer showed DTNB gene amplification -
Gene Info — DTNB
Entrez GeneID
1838Gene Name
DTNB
Gene Alias
MGC17163, MGC57126
Gene Description
dystrobrevin, beta
Omim ID
602415Gene Ontology
HyperlinkGene Summary
This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
-
-
Interactome
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com