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Last updated: 2014/12/14

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CHGA-ITPK1/CEN14q FISH Probe

  • Catalog # : FG0032
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Labeled FISH probes for identification of gene amplification using Fluoresecent In Situ Hybridization Technique. (Technology)
    The 50 uL format is now available until 2014/12/31, this format does not contain DAPI Counterstain. (Please contact us for more information.)
  • Quality Control Testing:
  • Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.

    QC Testing of FG0032
  • Supplied Product:
  • DAPI Counterstain (1500 ng/mL ) 250 uL
  • Storage Instruction:
  • Store at 4°C in the dark.
  • Note:

  • Hybridization position of the probes on the chromosome.

  • Probe 1:
        Size:
        Fluorophore:
        Location:
  • CHGA-ITPK1
    Approximately 270kb
    Texas Red
    14q32
  • Probe 2:
        Size:
        Fluorophore:
        Location:
  • CEN14q
    Approximately 400kb
    FITC
    14q11.2
  • Probe Gap:
  • The gap between two probes is approximately 59,900 kb.
  • Origin:
  • Human
  • Source:
  • Genomic DNA
  • Notice:
  • We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
  • Regulation Status:
  • For research use only (RUO)
  • Publication Reference
  • Applications
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections) enlargeenlarge this image
  • Human lung cancer (FFPE) stained with CHGA-ITPK1/CEN14q FISH Probe. Human lung cancer showed CHGA-ITPK1 gene amplification (CHGA-ITPK1/CEN14q ratio ≥ 2).
  • Protocol Download
  • Application Image
  • Fluorescent In Situ Hybridization (Cell)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 1113
  • Gene Name:
  • CHGA
  • Gene Alias:
  • CGA
  • Gene Description:
  • chromogranin A (parathyroid secretory protein 1)
  • Gene Summary:
  • The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown. [provided by RefSeq
  • Other Designations:
  • betagranin (N-terminal fragment of chromogranin A),chromogranin A,parathyroid secretory protein 1
  • Gene Information
  • Entrez GeneID:
  • 3705
  • Gene Name:
  • ITPK1
  • Gene Alias:
  • ITRPK1
  • Gene Description:
  • inositol 1,3,4-triphosphate 5/6 kinase
  • Other Designations:
  • inositol 1,3,4-trisphosphate 5/6 kinase,inositol-tetrakisphosphate 1-kinase
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