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BIRC3/MALT1,DY Translocation FISH Probe

  • Catalog # : FA0633
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Made to order FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. (Technology)
  • Supplied Product:
  • DAPI Counterstain (150 ng/mL) 250 uL
  • Storage Instruction:
  • Store at 4°C in the dark.
  • Origin:
  • Human
  • Source:
  • Genomic DNA
  • Notice:
  • We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Application Image
  • Fluorescent In Situ Hybridization (Cell)
  • Gene Information
  • Entrez GeneID:
  • 330
  • Gene Name:
  • BIRC3
  • Gene Alias:
  • AIP1,API2,CIAP2,HAIP1,HIAP1,MALT2,MIHC,RNF49
  • Gene Description:
  • baculoviral IAP repeat-containing 3
  • Gene Summary:
  • The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq
  • Other Designations:
  • TNFR2-TRAF signaling complex protein,apoptosis inhibitor 2,baculoviral IAP repeat-containing protein 3,inhibitor of apoptosis protein 1,mammalian IAP homolog C
  • Gene Information
  • Gene Name:
  • MALT1
  • Gene Alias:
  • DKFZp434L132,MLT,MLT1
  • Gene Description:
  • mucosa associated lymphoid tissue lymphoma translocation gene 1
  • Gene Summary:
  • This gene has been found to be recurrently rearranged in chromosomal translocation with two other genes - baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus - in mucosa-associated lymphoid tissue lymphomas. The protein encoded by this gene may play a role in NF-kappaB activation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
  • Other Designations:
  • MALT associated translocation,MALT-lymphoma associated translocation,caspase-like protein,mucosa associated lymphoid tissue lymphoma translocation protein 1,paracaspase
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