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Last updated: 2016/10/23

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  • Catalog # : FA0459
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  • Specification
  • Product Description:
  • Made to order FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. (Technology)
  • Supplied Product:
  • DAPI Counterstain (1500 ng/mL ) 250 uL
  • Storage Instruction:
  • Store at 4°C in the dark.
  • Origin:
  • Human
  • Source:
  • Genomic DNA
  • Notice:
  • We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Application Image
  • Fluorescent In Situ Hybridization (Cell)
  • Gene Information
  • Gene Name:
  • MKL1
  • Gene Alias:
  • Gene Description:
  • megakaryoblastic leukemia (translocation) 1
  • Gene Summary:
  • The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000028831,RBM15/MKL1 fusion,RNA-binding motif protein 15/megakaryoblastic leukemia-1 fusion protein,basic, SAP and coiled-coil domain,megakaryoblastic leukemia 1,megakaryoblastic leukemia 1 protein,megakaryocytic acute leukemia,myocardin-related
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