Products

Fluorescent In Situ Hybridization (Cell)

Entrez GeneID

Gene Name

PTPRG

Gene Alias

HPTPG, PTPG, R-PTP-GAMMA, RPTPG

Gene Description

protein tyrosine phosphatase, receptor type, G

Omim ID

Gene Ontology

Gene Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene. [provided by RefSeq

Other Designations

H_RG317H01.1|protein tyrosine phosphatase gamma|protein tyrosine phosphatase, receptor type, gamma polypeptide|receptor type protein tyrosine phosphatase gamma|receptor tyrosine phosphatase gamma|receptor-type protein phosphatase gamma