TPM3 FISH Probe
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Specification
Product Description
Made to order FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. (Technology).
Origin
Human
Source
Genomic DNA
Reactivity
Human
Notice
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
Regulation Status
For research use only (RUO)
Supplied Product
DAPI Counterstain (1500 ng/mL ) 250 uL
Storage Instruction
Store at 4°C in the dark.
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Applications
Fluorescent In Situ Hybridization (Cell)
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Gene Info — TPM3
Entrez GeneID
7170Gene Name
TPM3
Gene Alias
FLJ41118, MGC14582, MGC3261, MGC72094, NEM1, OK/SW-cl.5, TM-5, TM3, TM30, TM30nm, TPMsk3, TRK, hscp30
Gene Description
tropomyosin 3
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000034019|OTTHUMP00000034171|OTTHUMP00000034172|cytoskeletal tropomyosin TM30|heat-stable cytoskeletal protein 30 kDa|tropomyosin alpha-3 chain|tropomyosin gamma
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