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Last updated: 2017/7/23
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NFKB1 & HSPA1L Protein Protein Interaction Antibody Pair

  • Catalog # : DI0528
  • Visit Frequency :
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  • Specification
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Protein protein interaction immunofluorescence result.

    QC Testing of DI0528
    Representative image of Proximity Ligation Assay of protein-protein interactions between NFKB1 and HSPA1L. HeLa cells were stained with anti-NFKB1 rabbit purified polyclonal antibody 1:1200 and anti-HSPA1L mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex. The images were analyzed using an optimized freeware (BlobFinder) download from The Centre for Image Analysis at Uppsala University.
  • Supplied Product:
  • Antibody pair set content:
    1. NFKB1 rabbit purified polyclonal antibody (20 ug)
    2. HSPA1L mouse monoclonal antibody (40 ug)
    *Reagents are sufficient for at least 30-50 assays using recommended protocols.
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Publication Reference
  • Applications
  • In situ Proximity Ligation Assay (Cell)
  • Application Image
  • In situ Proximity Ligation Assay (Cell)
  • Gene Information
  • Entrez GeneID:
  • 4790
  • Gene Name:
  • NFKB1
  • Gene Alias:
  • DKFZp686C01211,EBP-1,KBF1,MGC54151,NF-kappa-B,NFKB-p105,NFKB-p50,p105,p50
  • Gene Description:
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
  • Gene Summary:
  • This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • DNA binding factor KBF1,NF-kappabeta,nuclear factor NF-kappa-B p50 subunit,nuclear factor kappa-B DNA binding subunit,nuclear factor kappa-B, subunit 1
  • Gene Information
  • Entrez GeneID:
  • 3305
  • Gene Name:
  • HSPA1L
  • Gene Alias:
  • HSP70-1L,HSP70-HOM,HSP70T,hum70t
  • Gene Description:
  • heat shock 70kDa protein 1-like
  • Gene Summary:
  • This gene encodes a 70kDa heat shock protein. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which also encode isoforms of the 70kDa heat shock protein. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000029295,heat shock 10kDa protein 1-like,heat shock 70kD protein-like 1
  • Interactome
  • Interactome
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