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APC & CSNK2A1 Protein Protein Interaction Antibody Pair

  • Catalog # : DI0449
  • Visit Frequency :
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  • Specification
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Protein protein interaction immunofluorescence result.

    QC Testing of DI0449
    Representative image of Proximity Ligation Assay of protein-protein interactions between APC and CSNK2A1. HeLa cells were stained with anti-APC rabbit purified polyclonal antibody 1:1200 and anti-CSNK2A1 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex. The images were analyzed using an optimized freeware (BlobFinder) download from The Centre for Image Analysis at Uppsala University.
  • Supplied Product:
  • Antibody pair set content:
    1. APC rabbit purified polyclonal antibody (20 ug)
    2. CSNK2A1 mouse monoclonal antibody (40 ug)
    *Reagents are sufficient for at least 30-50 assays using recommended protocols.
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Publication Reference
  • Applications
  • In situ Proximity Ligation Assay (Cell)
  • Application Image
  • In situ Proximity Ligation Assay (Cell)
  • Gene Information
  • Entrez GeneID:
  • 324
  • Gene Name:
  • APC
  • Gene Alias:
  • BTPS2,DP2,DP2.5,DP3,GS
  • Gene Description:
  • adenomatous polyposis coli
  • Gene Summary:
  • This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq
  • Other Designations:
  • adenomatosis polyposis coli tumor suppressor
  • Gene Information
  • Entrez GeneID:
  • 1457
  • Gene Name:
  • CSNK2A1
  • Gene Alias:
  • CK2A1,CKII
  • Gene Description:
  • casein kinase 2, alpha 1 polypeptide
  • Gene Summary:
  • Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. While this gene is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for this gene. [provided by RefSeq
  • Other Designations:
  • CK2 catalytic subunit alpha,OTTHUMP00000029925,OTTHUMP00000029926,casein kinase II alpha 1 subunit,casein kinase II alpha subunit,protein kinase CK2
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