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PIAS2 & PIAS1 Protein Protein Interaction Antibody Pair

  • Catalog # : DI0331
  • Visit Frequency :
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  • Specification
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Protein protein interaction immunofluorescence result.

    QC Testing of DI0331
    Representative image of Proximity Ligation Assay of protein-protein interactions between PIAS2 and PIAS1. HeLa cells were stained with anti-PIAS2 rabbit purified polyclonal antibody 1:1200 and anti-PIAS1 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex. The images were analyzed using an optimized freeware (BlobFinder) download from The Centre for Image Analysis at Uppsala University.
  • Supplied Product:
  • Antibody pair set content:
    1. PIAS2 rabbit purified polyclonal antibody (20 ug)
    2. PIAS1 mouse monoclonal antibody (40 ug)
    *Reagents are sufficient for at least 30-50 assays using recommended protocols.
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Publication Reference
  • Applications
  • In situ Proximity Ligation Assay (Cell)
  • Application Image
  • In situ Proximity Ligation Assay (Cell)
  • Gene Information
  • Entrez GeneID:
  • 9063
  • Gene Name:
  • PIAS2
  • Gene Alias:
  • Gene Description:
  • protein inhibitor of activated STAT, 2
  • Gene Summary:
  • This gene encodes a protein involved in the regulation of transcription factors involved in MAP kinase signaling. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1. Two alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq
  • Other Designations:
  • Msx-interacting-zinc finger,protein inhibitor of activated STAT X,zinc finger, MIZ-type containing 4
  • Gene Information
  • Entrez GeneID:
  • 8554
  • Gene Name:
  • PIAS1
  • Gene Alias:
  • DDXBP1,GBP,GU/RH-II,MGC141878,MGC141879,ZMIZ3
  • Gene Description:
  • protein inhibitor of activated STAT, 1
  • Gene Summary:
  • This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis. [provided by RefSeq
  • Other Designations:
  • AR interacting protein,DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1,protein inhibitor of activated STAT-1,zinc finger, MIZ-type containing 3
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  • Interactome
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