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XIAP & CASP9 Protein Protein Interaction Antibody Pair

  • Catalog # : DI0293
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  • Specification
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Protein protein interaction immunofluorescence result.

    QC Testing of DI0293
    Representative image of Proximity Ligation Assay of protein-protein interactions between XIAP and CASP9. HeLa cells were stained with anti-XIAP rabbit purified polyclonal antibody 1:1200 and anti-CASP9 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex. The images were analyzed using an optimized freeware (BlobFinder) download from The Centre for Image Analysis at Uppsala University.
  • Supplied Product:
  • Antibody pair set content:
    1. XIAP rabbit purified polyclonal antibody (20 ug)
    2. CASP9 mouse monoclonal antibody (40 ug)
    *Reagents are sufficient for at least 30-50 assays using recommended protocols.
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Publication Reference
  • Applications
  • In situ Proximity Ligation Assay (Cell)
  • Application Image
  • In situ Proximity Ligation Assay (Cell)
  • Gene Information
  • Entrez GeneID:
  • 331
  • Gene Name:
  • XIAP
  • Gene Alias:
  • API3,BIRC4,ILP1,MIHA,XLP2
  • Gene Description:
  • X-linked inhibitor of apoptosis
  • Gene Summary:
  • The protein encoded by this gene is a member of a family of proteins which inhibit apoptosis through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2. This protein inhibits apoptosis induced by menadione, a potent inducer of free radicals, and ICE. It also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000023975,OTTHUMP00000196392,apoptosis inhibitor 3,baculoviral IAP repeat-containing 4,baculoviral IAP repeat-containing protein 4
  • Gene Information
  • Entrez GeneID:
  • 842
  • Gene Name:
  • CASP9
  • Gene Alias:
  • APAF-3,APAF3,CASPASE-9c,ICE-LAP6,MCH6
  • Gene Description:
  • caspase 9, apoptosis-related cysteine peptidase
  • Gene Summary:
  • This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two transcript variants which encode different isoforms. [provided by RefSeq
  • Other Designations:
  • ICE-like apoptotic protease 6,OTTHUMP00000002322,OTTHUMP00000002323,OTTHUMP00000044594,apoptotic protease MCH-6,apoptotic protease activating factor 3,caspase 9,caspase 9, apoptosis-related cysteine protease
  • Interactome
  • Interactome
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