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Last updated: 2017/7/23
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HNF4A & FOXO1 Protein Protein Interaction Antibody Pair

  • Catalog # : DI0218
  • Visit Frequency :
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  • Specification
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Protein protein interaction immunofluorescence result.

    QC Testing of DI0218
    Representative image of Proximity Ligation Assay of protein-protein interactions between HNF4A and FOXO1. HeLa cells were stained with anti-HNF4A rabbit purified polyclonal antibody 1:1200 and anti-FOXO1 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex. The images were analyzed using an optimized freeware (BlobFinder) download from The Centre for Image Analysis at Uppsala University.
  • Supplied Product:
  • Antibody pair set content:
    1. HNF4A rabbit purified polyclonal antibody (20 ug)
    2. FOXO1 mouse monoclonal antibody (40 ug)
    *Reagents are sufficient for at least 30-50 assays using recommended protocols.
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Publication Reference
  • Applications
  • In situ Proximity Ligation Assay (Cell)
  • Application Image
  • In situ Proximity Ligation Assay (Cell)
  • Gene Information
  • Entrez GeneID:
  • 3172
  • Gene Name:
  • HNF4A
  • Gene Alias:
  • FLJ39654,HNF4,HNF4a7,HNF4a8,HNF4a9,MODY,MODY1,NR2A1,NR2A21,TCF,TCF14
  • Gene Description:
  • hepatocyte nuclear factor 4, alpha
  • Gene Summary:
  • The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq
  • Other Designations:
  • HNF4-alpha,OTTHUMP00000031060,OTTHUMP00000031062,hepatic nuclear factor 4 alpha,hepatocyte nuclear factor 4 alpha,transcription factor-14
  • Gene Information
  • Entrez GeneID:
  • 2308
  • Gene Name:
  • FOXO1
  • Gene Alias:
  • FKH1,FKHR,FOXO1A
  • Gene Description:
  • forkhead box O1
  • Gene Summary:
  • This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000018301,forkhead box O1A (rhabdomyosarcoma),forkhead homolog in rhabdomyosarcoma,forkhead, Drosophila, homolog of, in rhabdomyosarcoma
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  • Interactome
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