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Last updated: 2017/1/15
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HSP90AB1 & FLNA Protein Protein Interaction Antibody Pair

  • Catalog # : DI0206
  • Visit Frequency :
  • Countries :
  • Specification
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Protein protein interaction immunofluorescence result.

    QC Testing of DI0206
    Representative image of Proximity Ligation Assay of protein-protein interactions between HSP90AB1 and FLNA. HeLa cells were stained with anti-HSP90AB1 rabbit purified polyclonal antibody 1:1200 and anti-FLNA mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex. The images were analyzed using an optimized freeware (BlobFinder) download from The Centre for Image Analysis at Uppsala University.
  • Supplied Product:
  • Antibody pair set content:
    1. HSP90AB1 rabbit purified polyclonal antibody (20 ug)
    2. FLNA mouse monoclonal antibody (40 ug)
    *Reagents are sufficient for at least 30-50 assays using recommended protocols.
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Publication Reference
  • Applications
  • In situ Proximity Ligation Assay (Cell)
  • Application Image
  • In situ Proximity Ligation Assay (Cell)
  • Gene Information
  • Entrez GeneID:
  • 3326
  • Gene Name:
  • HSP90AB1
  • Gene Alias:
  • D6S182,FLJ26984,HSP90-BETA,HSP90B,HSPC2,HSPCB
  • Gene Description:
  • heat shock protein 90kDa alpha (cytosolic), class B member 1
  • Gene Summary:
  • HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. There are 2 major cytosolic HSP90 proteins, HSP90AA1 (MIM 140571), an inducible form, and HSP90AB1, a constitutive form. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1; MIM 191175) and mitochondria (TRAP1; MIM 606219) (Chen et al., 2005 [PubMed 16269234]).[supplied by OMIM
  • Other Designations:
  • OTTHUMP00000016517,OTTHUMP00000016518,OTTHUMP00000016519,OTTHUMP00000039869,heat shock 90kD protein 1, beta,heat shock 90kDa protein 1, beta,heat shock protein beta
  • Gene Information
  • Entrez GeneID:
  • 2316
  • Gene Name:
  • FLNA
  • Gene Alias:
  • ABP-280,ABPX,DKFZp434P031,FLN,FLN1,FMD,MNS,NHBP,OPD,OPD1,OPD2
  • Gene Description:
  • filamin A, alpha (actin binding protein 280)
  • Gene Summary:
  • The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene
  • Other Designations:
  • OTTHUMP00000024320,actin-binding protein 280,filamin 1,filamin A, alpha
  • Interactome 1
  • Interactome
  • Interactome 2
  • Interactome
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