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Scientific Image Contest
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FCGR3A & FCGR1A Protein Protein Interaction Antibody Pair

  • Catalog # : DI0195
  • Visit Frequency :
  • Countries :
  • Specification
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Protein protein interaction immunofluorescence result.

    QC Testing of DI0195
    Representative image of Proximity Ligation Assay of protein-protein interactions between FCGR3A and FCGR1A. HeLa cells were stained with anti-FCGR3A rabbit purified polyclonal antibody 1:1200 and anti-FCGR1A mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex. The images were analyzed using an optimized freeware (BlobFinder) download from The Centre for Image Analysis at Uppsala University.
  • Supplied Product:
  • Antibody pair set content:
    1. FCGR3A rabbit purified polyclonal antibody (20 ug)
    2. FCGR1A mouse monoclonal antibody (40 ug)
    *Reagents are sufficient for at least 30-50 assays using recommended protocols.
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Publication Reference
  • Applications
  • In situ Proximity Ligation Assay (Cell)
  • Application Image
  • In situ Proximity Ligation Assay (Cell)
  • Gene Information
  • Entrez GeneID:
  • 2214
  • Gene Name:
  • FCGR3A
  • Gene Alias:
  • CD16,CD16A,FCG3,FCGR3,FCGRIII,FCR-10,FCRIII,FCRIIIA,IGFR3
  • Gene Description:
  • Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
  • Gene Summary:
  • This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • Fc fragment of IgG, low affinity III, receptor for (CD16),Fc fragment of IgG, low affinity IIIa, receptor for (CD16),Fc gamma receptor III-A,Fc-gamma RIII-alpha,Fc-gamma RIIIa,Fc-gamma receptor III-2 (CD 16),Fc-gamma receptor IIIb (CD16),FcgammaRIIIA,OTTH
  • Gene Information
  • Entrez GeneID:
  • 2209
  • Gene Name:
  • FCGR1A
  • Gene Alias:
  • CD64,CD64A,FCRI,FLJ18345,IGFR1
  • Gene Description:
  • Fc fragment of IgG, high affinity Ia, receptor (CD64)
  • Gene Summary:
  • This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1. [provided by RefSeq
  • Other Designations:
  • Fc fragment of IgG, high affinity Ia, receptor for (CD64),Fc gamma receptor,Fc-gamma RI,Fc-gamma receptor I A1,IgG Fc receptor I,OTTHUMP00000013913
  • Interactome 1
  • Interactome
  • Interactome 2
  • Interactome
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