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Last updated: 2017/6/18
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Scientific Image Contest
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WEE1 & FBXW11 Protein Protein Interaction Antibody Pair

  • Catalog # : DI0193
  • Visit Frequency :
  • Countries :
  • Specification
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Protein protein interaction immunofluorescence result.

    QC Testing of DI0193
    Representative image of Proximity Ligation Assay of protein-protein interactions between WEE1 and FBXW11. HeLa cells were stained with anti-WEE1 rabbit purified polyclonal antibody 1:1200 and anti-FBXW11 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex. The images were analyzed using an optimized freeware (BlobFinder) download from The Centre for Image Analysis at Uppsala University.
  • Supplied Product:
  • Antibody pair set content:
    1. WEE1 rabbit purified polyclonal antibody (20 ug)
    2. FBXW11 mouse monoclonal antibody (40 ug)
    *Reagents are sufficient for at least 30-50 assays using recommended protocols.
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Publication Reference
  • Applications
  • In situ Proximity Ligation Assay (Cell)
  • Application Image
  • In situ Proximity Ligation Assay (Cell)
  • Gene Information
  • Entrez GeneID:
  • 7465
  • Gene Name:
  • WEE1
  • Gene Alias:
  • DKFZp686I18166,FLJ16446,WEE1A,WEE1hu
  • Gene Description:
  • WEE1 homolog (S. pombe)
  • Gene Summary:
  • This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase. [provided by RefSeq
  • Other Designations:
  • WEE1+ homolog,wee1 tyrosine kinase,wee1-like protein kinase
  • Gene Information
  • Gene Name:
  • FBXW11
  • Gene Alias:
  • BTRC2,BTRCP2,FBW1B,FBXW1B,Fbw11,Hos,KIAA0696
  • Gene Description:
  • F-box and WD repeat domain containing 11
  • Gene Summary:
  • This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. [provided by RefSeq
  • Other Designations:
  • F-box and WD-40 domain protein 11,F-box and WD-40 domain protein 1B,F-box protein Fbw1b,beta-transducin repeat-containing protein 2
  • Interactome 1
  • Interactome
  • Interactome 2
  • Interactome
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