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Last updated: 2017/8/13
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FGA & F2 Protein Protein Interaction Antibody Pair

  • Catalog # : DI0174
  • Visit Frequency :
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  • Specification
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Protein protein interaction immunofluorescence result.

    QC Testing of DI0174
    Representative image of Proximity Ligation Assay of protein-protein interactions between FGA and F2. HeLa cells were stained with anti-FGA rabbit purified polyclonal antibody 1:1200 and anti-F2 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex. The images were analyzed using an optimized freeware (BlobFinder) download from The Centre for Image Analysis at Uppsala University.
  • Supplied Product:
  • Antibody pair set content:
    1. FGA rabbit purified polyclonal antibody (20 ug)
    2. F2 mouse monoclonal antibody (40 ug)
    *Reagents are sufficient for at least 30-50 assays using recommended protocols.
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Publication Reference
  • Applications
  • In situ Proximity Ligation Assay (Cell)
  • Application Image
  • In situ Proximity Ligation Assay (Cell)
  • Gene Information
  • Entrez GeneID:
  • 2243
  • Gene Name:
  • FGA
  • Gene Alias:
  • Fib2,MGC119422,MGC119423,MGC119425
  • Gene Description:
  • fibrinogen alpha chain
  • Gene Summary:
  • The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus. [provided by RefSeq
  • Other Designations:
  • fibrinogen, A alpha polypeptide,fibrinogen, alpha chain, isoform alpha preproprotein,fibrinogen, alpha polypeptide
  • Gene Information
  • Entrez GeneID:
  • 2147
  • Gene Name:
  • F2
  • Gene Alias:
  • PT
  • Gene Description:
  • coagulation factor II (thrombin)
  • Gene Summary:
  • Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia. [provided by RefSeq
  • Other Designations:
  • coagulation factor II,prothrombin B-chain,serine protease
  • Interactome 1
  • Interactome
  • Interactome 2
  • Interactome
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