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Last updated: 2017/8/20

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ACTN1 & CTNNA1 Protein Protein Interaction Antibody Pair

  • Catalog # : DI0141
  • Visit Frequency :
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  • Specification
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Protein protein interaction immunofluorescence result.

    QC Testing of DI0141
    Representative image of Proximity Ligation Assay of protein-protein interactions between ACTN1 and CTNNA1. HeLa cells were stained with anti-ACTN1 rabbit purified polyclonal antibody 1:1200 and anti-CTNNA1 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex. The images were analyzed using an optimized freeware (BlobFinder) download from The Centre for Image Analysis at Uppsala University.
  • Supplied Product:
  • Antibody pair set content:
    1. ACTN1 rabbit purified polyclonal antibody (20 ug)
    2. CTNNA1 mouse monoclonal antibody (40 ug)
    *Reagents are sufficient for at least 30-50 assays using recommended protocols.
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Publication Reference
  • Applications
  • In situ Proximity Ligation Assay (Cell)
  • Application Image
  • In situ Proximity Ligation Assay (Cell)
  • Gene Information
  • Entrez GeneID:
  • 87
  • Gene Name:
  • ACTN1
  • Gene Alias:
  • FLJ40884
  • Gene Description:
  • actinin, alpha 1
  • Gene Summary:
  • Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • F-actin cross-linking protein,actinin 1 smooth muscle,alpha-actinin 1
  • Gene Information
  • Entrez GeneID:
  • 1495
  • Gene Name:
  • CTNNA1
  • Gene Alias:
  • CAP102,FLJ36832
  • Gene Description:
  • catenin (cadherin-associated protein), alpha 1, 102kDa
  • Other Designations:
  • alpha-E-catenin,alpha-catenin,alphaE-catenin,cadherin-associated protein,102kDa,catenin (cadherin-associated protein), alpha 1 (102kD),catenin, alpha 1
  • Interactome 1
  • Interactome
  • Interactome 2
  • Interactome
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