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Last updated: 2017/7/23
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FYN & CTLA4 Protein Protein Interaction Antibody Pair

  • Catalog # : DI0137
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  • Specification
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Protein protein interaction immunofluorescence result.

    QC Testing of DI0137
    Representative image of Proximity Ligation Assay of protein-protein interactions between FYN and CTLA4. HeLa cells were stained with anti-FYN rabbit purified polyclonal antibody 1:1200 and anti-CTLA4 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex. The images were analyzed using an optimized freeware (BlobFinder) download from The Centre for Image Analysis at Uppsala University.
  • Supplied Product:
  • Antibody pair set content:
    1. FYN rabbit purified polyclonal antibody (20 ug)
    2. CTLA4 mouse monoclonal antibody (40 ug)
    *Reagents are sufficient for at least 30-50 assays using recommended protocols.
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Publication Reference
  • Applications
  • In situ Proximity Ligation Assay (Cell)
  • Application Image
  • In situ Proximity Ligation Assay (Cell)
  • Gene Information
  • Entrez GeneID:
  • 2534
  • Gene Name:
  • FYN
  • Gene Alias:
  • MGC45350,SLK,SYN
  • Gene Description:
  • FYN oncogene related to SRC, FGR, YES
  • Gene Summary:
  • This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist. [provided by RefSeq
  • Other Designations:
  • OKT3-induced calcium influx regulator,OTTHUMP00000017914,OTTHUMP00000017915,OTTHUMP00000017917,c-syn protooncogene,protein-tyrosine kinase fyn,proto-oncogene tyrosine-protein kinase fyn,src-like kinase,src/yes-related novel,tyrosine kinase p59fyn(T)
  • Gene Information
  • Entrez GeneID:
  • 1493
  • Gene Name:
  • CTLA4
  • Gene Alias:
  • CD152,CELIAC3,CTLA-4,GSE,IDDM12
  • Gene Description:
  • cytotoxic T-lymphocyte-associated protein 4
  • Gene Summary:
  • This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000163781,cytotoxic T-lymphocyte-associated antigen 4,cytotoxic T-lymphocyte-associated serine esterase-4,ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4
  • Interactome 1
  • Interactome
  • Interactome 2
  • Interactome
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