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BACE1 & CSNK1D Protein Protein Interaction Antibody Pair

  • Catalog # : DI0131
  • Visit Frequency :
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  • Specification
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Protein protein interaction immunofluorescence result.

    QC Testing of DI0131
    Representative image of Proximity Ligation Assay of protein-protein interactions between BACE1 and CSNK1D. HeLa cells were stained with anti-BACE1 rabbit purified polyclonal antibody 1:1200 and anti-CSNK1D mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex. The images were analyzed using an optimized freeware (BlobFinder) download from The Centre for Image Analysis at Uppsala University.
  • Supplied Product:
  • Antibody pair set content:
    1. BACE1 rabbit purified polyclonal antibody (20 ug)
    2. CSNK1D mouse monoclonal antibody (40 ug)
    *Reagents are sufficient for at least 30-50 assays using recommended protocols.
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Publication Reference
  • Applications
  • In situ Proximity Ligation Assay (Cell)
  • Application Image
  • In situ Proximity Ligation Assay (Cell)
  • Gene Information
  • Gene Name:
  • BACE1
  • Gene Alias:
  • ASP2,BACE,FLJ90568,HSPC104,KIAA1149
  • Gene Description:
  • beta-site APP-cleaving enzyme 1
  • Gene Summary:
  • Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
  • Other Designations:
  • APP beta-secretase,aspartyl protease 2,beta-secretase,beta-site amyloid beta A4 precursor protein-cleaving enzyme,beta-site amyloid precursor protein cleaving enzyme,memapsin-2,membrane-associated aspartic protease 2,transmembrane aspartic proteinase Asp2
  • Gene Information
  • Entrez GeneID:
  • 1453
  • Gene Name:
  • CSNK1D
  • Gene Alias:
  • HCKID
  • Gene Description:
  • casein kinase 1, delta
  • Gene Summary:
  • This gene is a member of the casein kinase I (CKI) gene family whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is highly similar to the mouse and rat CK1 delta homologs. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
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