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SYK & CTTN Protein Protein Interaction Antibody Pair

  • Catalog # : DI0128
  • Visit Frequency :
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  • Specification
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Protein protein interaction immunofluorescence result.

    QC Testing of DI0128
    Representative image of Proximity Ligation Assay of protein-protein interactions between SYK and CTTN. HeLa cells were stained with anti-SYK rabbit purified polyclonal antibody 1:1200 and anti-CTTN mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex. The images were analyzed using an optimized freeware (BlobFinder) download from The Centre for Image Analysis at Uppsala University.
  • Supplied Product:
  • Antibody pair set content:
    1. SYK rabbit purified polyclonal antibody (20 ug)
    2. CTTN mouse monoclonal antibody (40 ug)
    *Reagents are sufficient for at least 30-50 assays using recommended protocols.
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Publication Reference
  • Applications
  • In situ Proximity Ligation Assay (Cell)
  • Application Image
  • In situ Proximity Ligation Assay (Cell)
  • Gene Information
  • Entrez GeneID:
  • 6850
  • Gene Name:
  • SYK
  • Gene Alias:
  • DKFZp313N1010,FLJ25043,FLJ37489
  • Gene Description:
  • spleen tyrosine kinase
  • Other Designations:
  • OTTHUMP00000021627,OTTHUMP00000021628
  • Gene Information
  • Entrez GeneID:
  • 2017
  • Gene Name:
  • CTTN
  • Gene Alias:
  • EMS1,FLJ34459
  • Gene Description:
  • cortactin
  • Gene Summary:
  • This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Two splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq
  • Other Designations:
  • 1110020L01Rik,ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate),oncogene EMS1
  • Interactome 1
  • Interactome
  • Interactome 2
  • Interactome
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