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CFLAR & CASP10 Protein Protein Interaction Antibody Pair

  • Catalog # : DI0078
  • Visit Frequency :
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  • Specification
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Protein protein interaction immunofluorescence result.

    QC Testing of DI0078
    Representative image of Proximity Ligation Assay of protein-protein interactions between CFLAR and CASP10. HeLa cells were stained with anti-CFLAR rabbit purified polyclonal antibody 1:1200 and anti-CASP10 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex. The images were analyzed using an optimized freeware (BlobFinder) download from The Centre for Image Analysis at Uppsala University.
  • Supplied Product:
  • Antibody pair set content:
    1. CFLAR rabbit purified polyclonal antibody (20 ug)
    2. CASP10 mouse monoclonal antibody (40 ug)
    *Reagents are sufficient for at least 30-50 assays using recommended protocols.
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Publication Reference
  • Applications
  • In situ Proximity Ligation Assay (Cell)
  • Application Image
  • In situ Proximity Ligation Assay (Cell)
  • Gene Information
  • Entrez GeneID:
  • 8837
  • Gene Name:
  • CFLAR
  • Gene Alias:
  • CASH,CASP8AP1,CLARP,Casper,FLAME,FLAME-1,FLAME1,FLIP,I-FLICE,MRIT,c-FLIP,c-FLIPL,c-FLIPR,c-FLIPS
  • Gene Description:
  • CASP8 and FADD-like apoptosis regulator
  • Other Designations:
  • FADD-like anti-apoptotic molecule,caspase-related inducer of apoptosis,inhibitor of FLICE,usurpin beta
  • Gene Information
  • Entrez GeneID:
  • 843
  • Gene Name:
  • CASP10
  • Gene Alias:
  • ALPS2,FLICE2,MCH4
  • Gene Description:
  • caspase 10, apoptosis-related cysteine peptidase
  • Gene Summary:
  • This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
  • Other Designations:
  • FADD-like ICE2,Fas-associated death domain protein,ICE-like apoptotic protease 4,apoptotic protease MCH-4,caspase 10,caspase 10, apoptosis-related cysteine protease,interleukin-1B-converting enzyme 2
  • Interactome 1
  • Interactome
  • Interactome 2
  • Interactome
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