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Anti-CLDN1 monoclonal antibody

  • Catalog # : DH0015
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Anti-CLDN1 is intended for the semi-quantitative detection of Claudin 1 (CLDN1 ) in paraffin sections.
  • Immunogen:
  • CLDN1 (AAH12471.1, 1 a.a. ~ 211 a.a) recombinant protein with GST tag.
  • Host:
  • Mouse
  • Specificity:
  • Human Claudin 1
  • Isotype:
  • IgG2a Kappa
  • Storage Buffer:
  • In 1x PBS, pH 7.2
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Product image

  • Regulation Status:
  • USA:
    IVD Class 1
    (FDA Registered Establishment Number: 3007539499)

    Taiwan:
    產品名稱: 亞諾法免疫組織化學染色單株抗體 (未滅菌) (緊密連接蛋白1單株抗體)
    許可證字號: 衛署醫器製壹字第004544號 (醫療器材管理辦法「免疫組織化學試劑與套組(B.1860)」第一等級鑒別範圍)
  • Clone Name:
  • Monoclonal antibody (S4)
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) enlargeenlarge this image
  • Immunoperoxidase of monoclonal antibody to CLDN1 on formalin-fixed paraffin-embedded human colon cancer. [antibody concentration 3 ug/ml]
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 9076
  • Gene Name:
  • CLDN1
  • Gene Alias:
  • CLD1,ILVASC,SEMP1
  • Gene Description:
  • claudin 1
  • Gene Summary:
  • Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq
  • Other Designations:
  • senescence-associated epithelial membrane protein 1
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