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Anti-GBA monoclonal antibody

  • Catalog # : DH0011
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Anti-GBA is intended for the semi-quantitative detection of Glucosidase, Beta, Acid (GBA ) in paraffin sections.
  • Immunogen:
  • GBA (NP_000148.2, 146 a.a. ~ 235 a.a) recombinant protein with GST tag.
  • Host:
  • Mouse
  • Specificity:
  • Human Glucosidase, beta, acid
  • Isotype:
  • IgG2a Kappa
  • Storage Buffer:
  • In 1x PBS, pH 7.2
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Product image

  • Regulation Status:
  • USA:
    IVD Class 1
    (FDA Registered Establishment Number: 3007539499)

    Taiwan:
    產品名稱: 亞諾法免疫組織化學染色單株抗體 (未滅菌) (酸性β葡萄糖苷酶單株抗體)
    許可證字號: 衛署醫器製壹字第004544號 (醫療器材管理辦法「免疫組織化學試劑與套組(B.1860)」第一等級鑒別範圍)
  • Clone Name:
  • Monoclonal antibody (2E2)
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) enlargeenlarge this image
  • Immunoperoxidase of monoclonal antibody to GBA on formalin-fixed paraffin-embedded human breast cancer. [antibody concentration 3 ug/ml]
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) enlargeenlarge this image
  • Immunoperoxidase of monoclonal antibody to GBA on formalin-fixed paraffin-embedded human ovary cancer. [antibody concentration 3 ug/ml]
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 2629
  • Gene Name:
  • GBA
  • Gene Alias:
  • GBA1,GCB,GLUC
  • Gene Description:
  • glucosidase, beta; acid (includes glucosylceramidase)
  • Gene Summary:
  • This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq
  • Other Designations:
  • D-glucosyl-N-acylsphingosine glucohydrolase,OTTHUMP00000033992,OTTHUMP00000033993,glucocerebrosidase,glucocerebrosidase (alt.),lysosomal glucocerebrosidase
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