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Anti-STIP1 monoclonal antibody

  • Catalog # : DH0006
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Anti-STIP1 is intended for the semi-quantitative detection of Stress-induced-phosphoprotein 1 (STIP1) in paraffin sections.
  • Immunogen:
  • STIP1 (NP_006810.1, 445 a.a. ~ 543 a.a) partial recombinant protein with GST tag.
  • Host:
  • Mouse
  • Specificity:
  • Human Stress-induced-phosphoprotein 1
  • Isotype:
  • IgG2a Kappa
  • Storage Buffer:
  • In 1x PBS, pH 7.2
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Product image

  • Regulation Status:
  • USA:
    IVD Class 1
    (FDA Registered Establishment Number: 3007539499)

    Taiwan:
    產品名稱: 亞諾法免疫組織化學染色單株抗體 (未滅菌) (壓力誘導磷酸化蛋白單株抗體)
    許可證字號: 衛署醫器製壹字第004544號 (醫療器材管理辦法「免疫組織化學試劑與套組(B.1860)」第一等級鑒別範圍)
  • Clone Name:
  • Monoclonal antibody (1E3)
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) enlargeenlarge this image
  • Immunoperoxidase of monoclonal antibody to STIP1 on formalin-fixed paraffin-embedded human ovarian cancer. [antibody concentration 3 ug/ml]
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Gene Name:
  • STIP1
  • Gene Alias:
  • HOP,IEF-SSP-3521,P60,STI1,STI1L
  • Gene Description:
  • stress-induced-phosphoprotein 1
  • Gene Summary:
  • STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM
  • Other Designations:
  • Hsp70/Hsp90-organizing protein,stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein)
  • Gene Pathway
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