Product Browser

Last updated: 2016/12/4

Product Compare

Product Compare Cancel Click this icon to add products to compare list. Select up to 10 products.

Quick Order (Tutorial)

Input Catalog #,
place order here!
Catalog # :
  • Where to buy
  • Choose your location

Anti-TYMS monoclonal antibody

  • Catalog # : DH0004
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Anti-TYMS is intended for the semi-quantitative detection of Thymidylate Synthetase (TYMS) in paraffin sections.
  • Immunogen:
  • TYMS (AAH13919.1, 111 a.a. - 210 a.a) partial recombinant protein with GST tag.
  • Host:
  • Mouse
  • Specificity:
  • Human Thymidylate synthetase
  • Isotype:
  • IgG1 Kappa
  • Storage Buffer:
  • In 1x PBS, pH 7.2
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Product image

  • Regulation Status:
  • USA:
    IVD Class 1
    (FDA Registered Establishment Number: 3007539499)

    Taiwan:
    產品名稱: 亞諾法免疫組織化學染色單株抗體 (未滅菌) (胸苷酸合成酶單株抗體)
    許可證字號: 衛署醫器製壹字第004544號 (醫療器材管理辦法「免疫組織化學試劑與套組(B.1860)」第一等級鑒別範圍)
  • Clone Name:
  • Monoclonal antibody (3A1)
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) enlargeenlarge this image
  • Immunoperoxidase of monoclonal antibody to TYMS on formalin-fixed paraffin-embedded human lung adenocarcinoma. [antibody concentration 3 ug/ml]
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) enlargeenlarge this image
  • Immunoperoxidase of monoclonal antibody to TYMS on formalin-fixed paraffin-embedded human ovarian cancer. [antibody concentration 3 ug/ml]
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 7298
  • Gene Name:
  • TYMS
  • Gene Alias:
  • HsT422,MGC88736,TMS,TS,TSase
  • Gene Description:
  • thymidylate synthetase
  • Gene Summary:
  • Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase. [provided by RefSeq
  • Other Designations:
  • Thymidylate synthase
  • Related Disease
  • RSS
  • YouTube
  • Linkedin
  • Facebook