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Last updated: 2014/10/20
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BACE2 polyclonal antibody

  • Catalog # : PAB9773
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of BACE2.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 44-59 of human BACE2.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of BACE2 expression in human (lane 1) and mouse (lane 2) heart tissue in BACE2 polyclonal antibody.
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • BACE2
  • Gene Alias:
  • AEPLC,ALP56,ASP1,ASP21,BAE2,CDA13,CEAP1,DRAP
  • Gene Description:
  • beta-site APP-cleaving enzyme 2
  • Gene Summary:
  • Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by this gene. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease. Three transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
  • Other Designations:
  • 56 kDa aspartic-like protease,Down syndrome region aspartic protease,aspartyl protease 1,beta secretase 2,beta-site amyloid beta A4 precursor protein-cleaving enzyme 2,memapsin-1,membrane-associated aspartic protease 1,transmembrane aspartic proteinase As
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