GLI1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of GLI1 expression in RMS-13 (SJCRH30) lysate at 15 ug/lane with antibody used at 10 ug/mL.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of GLI1.
Immunogen
A synthetic peptide corresponding to human GLI1.
Host
Rabbit
Reactivity
Human
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.08% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of GLI1 expression in RMS-13 (SJCRH30) lysate at 15 ug/lane with antibody used at 10 ug/mL. -
Gene Info — GLI1
Entrez GeneID
2735Gene Name
GLI1
Gene Alias
GLI
Gene Description
glioma-associated oncogene homolog 1 (zinc finger protein)
Omim ID
165220Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
glioma-associated oncogene homolog (zinc finger protein)|glioma-associated oncogene homolog 1
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Interactome
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Pathway
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Disease
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Publication Reference
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Letters to the editor: identification of polymorphic variants of the GLI1 oncogene.
Wang XQ, Chan N, Rothnagel JA.
The Journal of Investigative Dermatology 2000 Aug; 115(2):328.
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The GLI gene is a member of the Kruppel family of zinc finger proteins.
Kinzler KW, Ruppert JM, Bigner SH, Vogelstein B.
Nature 1988 Mar; 332(6162):371.
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Letters to the editor: identification of polymorphic variants of the GLI1 oncogene.
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