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Last updated: 2014/4/21
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BIOtech
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MAPT polyclonal antibody

  • Catalog # : PAB8046
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  • Specification
  • Product Description:
  • Sheep polyclonal antibody raised against synthetic peptide of MAPT.
  • Immunogen:
  • A synthetic peptide (conjugated with diphtheria toxin) corresponding to human MAPT.
  • Sequence:
  • EDHAGTYGLGDRKDQGGYTC
  • Host:
  • Sheep
  • Reactivity:
  • Human
  • Form:
  • Lyophilized
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Immunofluorescence (1:400-1:800)
    Western Blot (1:2000-1:8000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from serum (0.02% thimerosal)
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with deionized water, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry using MAPT polyclonal antibody (Cat # PAB8046) showing excellent staining of MAPT aggregations within human neural tissue and within neuronal axons MAPT threads (arrows) in. It is light IHC using MAPT polyclonal antibody (Cat # PAB8046) (1/8000) with Jackson biotinylated donkey anti rabbit secondary antibody (1/2000) followed by Sigma Extra avidin peroxidase (1/400) and DAB substrate and a very light hematoxylin counter stain.
  • Immunofluorescence
  • Immunofluorescence
  • Immunohistochemistry using MAPT polyclonal antibody (Cat # PAB8046) showing excellent staining of MAPT aggregations within human neural tissue. It is a confocal IHC image of MAPT polyclonal antibody (Cat # PAB8046) at 1/400 dilution with Jackson Cy2 secondary antibody (1/100) .
  • ELISA
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 4137
  • Gene Name:
  • MAPT
  • Gene Alias:
  • DDPAC,FLJ31424,FTDP-17,MAPTL,MGC138549,MSTD,MTBT1,MTBT2,PPND,TAU
  • Gene Description:
  • microtubule-associated protein tau
  • Gene Summary:
  • This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq
  • Other Designations:
  • G protein beta1/gamma2 subunit-interacting factor 1,microtubule-associated protein tau, isoform 4
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