PRDX4 positive staining of sebaceous glands in rat skin. PRDX4 polyclonal antibody (Cat # PAB8031) (1/1000) ; secondary antibody Jackson biotinylated Donkey anti-rabbit (1/2000) followed by Vector ABC kit and visualised with DAB substrate.
PRDX4 staining in rat airways. Positive staining of Non-ciliated bronchiolar cells (Clara cells) in rat lung. PRDX4 polyclonal antibody (Cat # PAB8031) (1/100) ; secondary antibody Jackson Cy3 (1/200) .
The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB. [provided by RefSeq