EV71 VP1 polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against EV71 VP1 protein.
Immunogen
EV71 VP1 (1 a.a. ~ 297 a.a) full-length human protein.
Host
Rabbit
Reactivity
Viruses
Form
Liquid
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of EV71-VP1 expression in transfected 293T cell line by EV71-VP1 MaxPab polyclonal antibody.
Lane 1: EV71-VP1 transfected lysate(33.44 KDa).
Lane 2: Non-transfected lysate.
Detection Antibody
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Publication Reference
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Secreted LRPAP1 binds and triggers IFNAR1 degradation to facilitate virus evasion from cellular innate immunity.
Huangcan Li, Xiong Wang, Yiran Wang, Yichen Li, Ying Chen, Yin-Ting Wong, Jufang He, Ming-Liang He.
Signal Transduction and Targeted Therapy 2023 Sep; 8(1):374.
Application:IF, WB, Human, Mouse, HEK293T, Mouse intestine, RD cells.
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Featured interactome of homocysteine-inducible endoplasmic reticulum protein uncovers novel binding partners in response to ER stress.
Rui Su, Jialing Yin, Xiaolan Ruan, Yanxi Chen, Pin Wan, Zhen Luo.
Computational and Structural Biotechnology Journal 2023 Sep; 21:4478.
Application:WB, Human, HeLa cells.
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ML390 inhibits enterovirus 71 replication by targeting de novo pyrimidine biosynthesis pathway
Qingyu Yang, Chengyuan Wu, Guangyan Zhu, Fuli Ren, Binbin Lin, Rui Huang, Xujuan Hu, Dingran Zhao, Ke Peng, Ying Wu, Qiongya Wang, Chaolin Huang, Dingyu Zhang.
Antiviral Research 2023 Jan; 209:105498.
Application:WB-Ce, WB-Tr, Human, RD cells.
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Curcumin assists anti-EV71 activity of IFN-α by inhibiting IFNAR1 reduction in SH-SY5Y cells.
Yanfang Wang, Kena Dan, Xiaoling Xue, Bangtao Chen, Cheng Chen.
Gut Pathogens 2022 Feb; 14(1):8.
Application:WB-Ce, Human, SH-SY5Y cells.
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Role of IL-6-IL-27 Complex in Host Antiviral Immune Response.
Qi Zuo, Zhikui Cheng, Guoqing Zhang, Yongfang Xia, Gang Xu, Wei Cao, Xiaodan Yang, Yundong Fu, Rui He, Peining Fang, Yifei Guo, Longyu Nie, Yu Huang, Lin Liu, Jianbo Zhan, Shi Liu, Ying Zhu.
Journal of immunology 2021 Jun; ji2100179.
Application:WB-Tr, Human, RD cells.
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Inducible ATP1B1 Upregulates Antiviral Innate Immune Responses by the Ubiquitination of TRAF3 and TRAF6.
Wei Cao, Yifei Guo, Zhikui Cheng, Gang Xu, Qi Zuo, Longyu Nie, Yu Huang, Shi Liu, Ying Zhu.
Journal of immunology 2021 Jun; 206(11):2668.
Application:WB-Tr, Human, RD cells.
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MiR-103/miR-107 inhibits enterovirus 71 replication and facilitates type I interferon response by regulating SOCS3/STAT3 pathway.
Baizhi Huang, Haiping Chen, Yanbing Zheng.
Biotechnology Letters 2021 Jul; 43(7):1357.
Application:WB-Tr, Human, Monkey, VERO, RD cells.
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Beclin1 Binds to Enterovirus 71 3D Protein to Promote the Virus Replication.
Qi Xiang, Pin Wan, Ge Yang, Siyu Huang, Mengying Qin, Hua Yang, Zhen Luo, Kailang Wu, Jianguo Wu.
Viruses 2020 Jul; 12(7):E756.
Application:WB, Human, RD, U251 cells.
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Metabolic Reprogramming of Host Cells in Response to Enteroviral Infection.
Cheng ML, Chien KY, Lai CH, Li GJ, Lin JF, Ho HY.
Cells 2020 Feb; 9(2):E473.
Application:WB-Tr, Monkey, Vero cells.
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Hypoxia and therapeutic treatment of EV-A71 with an immune modulator TLR7 agonist in a new immunocompetent mouse model.
Liou AT, Liao CC, Chou SF, Chang YS, Chang CS, Shih C.
Journal of Biomedical Science 2019 Nov; 26(1):93.
Application:IHC-P, Mouse, Spleens.
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Cellular Caspase-3 Contributes to EV-A71 2Apro-Mediated Down-Regulation of IFNAR1 at the Translation Level.
Chen B, Wang Y, Pei X, Wang S, Zhang H, Peng Y.
Virologica Sinica 2019 Sep; [Epub].
Application:WB-Ce, Human, RD cells.
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Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex.
Xu G, Xia Z, Deng F, Liu L, Wang Q, Yu Y, Wang F, Zhu C, Liu W, Cheng Z, Zhu Y, Zhou L, Zhang Y, Lu M, Liu S.
PLoS Pathogens 2019 Aug; 15(8):e1008002.
Application:WB, Human, Mouse, MEFs, RD cells.
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Enterovirus 71 targets the cardiopulmonary system in a robust oral infection mouse model.
Chang CS, Liao CC, Liou AT, Chang YS, Chang YT, Tzeng BH, Chen CC, Shih C.
Scientific Reports 2019 Jul; 9(1):11108.
Application:IHC-P, Mouse, Hearts, Kidneys, Livers, Lungs, Muscles.
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NAC1 Potentiates Cellular Antiviral Signaling by Bridging MAVS and TBK1.
Xia Z, Xu G, Nie L, Liu L, Peng N, He Q, Zuo Q, Zhou Y, Cao Z, Liu S, Zhu Y.
Journal of immunology 2019 Aug; 203(4):1001.
Application:WB-Tr, Human, RD cells.
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Viral engagement with host (co-)receptors blocked by a novel class of tryptophan dendrimers that targets the 5-fold-axis of the enterovirus-A71 capsid.
Sun L, Lee H, Thibaut HJ, Lanko K, Rivero-Buceta E, Bator C, Martinez-Gualda B, Dallmeier K, Delang L, Leyssen P, Gago F, San-Félix A, Hafenstein S, Mirabelli C, Neyts J.
PLoS Pathogens 2019 May; 15(5):e1007760.
Application:WB-Tr, Human, HEK 293 cells.
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Polypyrimidine Tract-Binding Protein Regulates Enterovirus 71 Translation Through Interaction with the Internal Ribosomal Entry Site.
Xi J, Ye F, Wang G, Han W, Wei Z, Yin B, Yuan J, Qiang B, Peng X.
Virologica Sinica 2019 Feb; 34(1):66.
Application:WB, Human, T98G cells.
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Fibronectin facilitates EV71 infection by mediating its entry.
He QQ, Ren S, Xia ZC, Cheng ZK, Peng NF, Zhu Y.
Journal of Virology 2018 Apr; 92(9):e02251.
Application:IHC, WB-Ce, Mouse, Human, Mouse brainstem, skeletal muscle, RD, HEK293 cells.
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HERP Binds TBK1 To Activate Innate Immunity and Repress Virus Replication in Response to Endoplasmic Reticulum Stress.
Ge M, Luo Z, Qiao Z, Zhou Y, Cheng X, Geng Q, Cai Y, Wan P, Xiong Y, Liu F, Wu K, Liu Y, Wu J.
Journal of immunology 2017 Nov; 199(9):3280.
Application:WB-Tr, Human, HEK 293T cells, Human rhabdomyosarcoma (RD) cells.
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Berberine inhibits enterovirus 71 replication by downregulating the MEK/ERK signaling pathway and autophagy.
Wang H, Li K, Ma L, Wu S, Hu J, Yan H, Jiang J, Li Y.
Virology Journal 2017 Jan; 14(1):2.
Application:WB, Monkey, Vero cells.
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A new animal model containing human SCARB2 and lacking stat-1 is highly susceptible to EV71.
Liou AT, Wu SY, Liao CC, Chang YS, Chang CS, Shih C.
Scientific Reports 2016 Aug; 6:31151.
Application:IHC, Mouse, Brain, Spinal cord.
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Early growth response-1 facilitates enterovirus 71 replication by direct binding to the viral genome RNA.
Song Y, Cheng X, Yang X, Zhao R, Wang P, Han Y, Luo Z, Cao Y, Zhu C, Xiong Y, Liu Y, Wu K, Wu J.
The International Journal of Biochemistry & Cell Biology 2015 May; 62:36.
Application:WB-Tr, Human, RD, SK-N-SH cells.
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PolyC-Binding Protein 1 Interacts with 5'-Untranslated Region of Enterovirus 71 RNA in Membrane-Associated Complex to Facilitate Viral Replication.
Luo Z, Dong X, Li Y, Zhang Q, Kim C, Song Y, Kang L, Liu Y, Wu K, Wu J.
PLoS One 2014 Jan; 9(1):e87491.
Application:WB-Tr, Human, RD cells.
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Human enterovirus 71 uncoating captured at atomic resolution.
Lyu K, Ding J, Han JF, Zhang Y, Wu XY, He YL, Qin CF, Chen R.
Journal of Virology 2014 Mar; 88(6):3114.
Application:WB-Ce, Virus, EV71 strain AH08/06.
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The highly conserved 5' untranslated region as an effective target towards the inhibition of Enterovirus 71 replication by unmodified and appropriate 2'-modified siRNAs.
Deng JX, Nie XJ, Lei YF, Ma CF, Xu DL, Li B, Xu ZK, Zhang GC.
Journal of Biomedical Science 2012 Aug; 19:73.
Application:WB-Ce, Human, RD cells.
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Enterovirus 71 Disrupts Interferon Signaling by reducing the Interferon Receptor I.
Lu J, Yi L, Zhao J, Yu J, Chen Y, Lin MC, Kung HF, He ML.
Journal of Virology 2012 Jan; 86(7):3767.
Application:WB, Viruses, Viral structure protein.
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Viral kinetics of Enterovirus 71 in human abdomyosarcoma cells.
Lu J, He YQ, Yi LN, Zan H, Kung HF, He ML.
World Journal of Gastroenterology 2011 Sep; 17(36):4135.
Application:WB-Tr, Human, Rhabdomyosarcoma cells.
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Secreted LRPAP1 binds and triggers IFNAR1 degradation to facilitate virus evasion from cellular innate immunity.
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