KCNB1 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of KCNB1.
Immunogen
A synthetic peptide corresponding to human KCNB1.
Sequence
C-HQYIDADTDDEGQ
Host
Goat
Theoretical MW (kDa)
95.9
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:4000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — KCNB1
Entrez GeneID
3745Protein Accession#
NP_004966.1Gene Name
KCNB1
Gene Alias
DRK1, KV2.1, h-DRK1
Gene Description
potassium voltage-gated channel, Shab-related subfamily, member 1
Omim ID
600397Gene Ontology
HyperlinkGene Summary
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members. [provided by RefSeq
Other Designations
OTTHUMP00000031697|delayed rectifier potassium channel Kv2.1|h-DRK1 K(+) channel|potassium channel protein DRK1|potassium voltage-gated channel subfamily B member 1|voltage-gated potassium channel
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Interactome
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Pathway
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Disease
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Publication Reference
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Graded regulation of the Kv2.1 potassium channel by variable phosphorylation.
Park KS, Mohapatra DP, Misonou H, Trimmer JS.
Science 2006 Aug; 313(5789):976.
Application：WB-Tr, Human, HEK 293 cells.
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Graded regulation of the Kv2.1 potassium channel by variable phosphorylation.
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