HOXA5 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of HOXA5.
Immunogen
A synthetic peptide corresponding to human HOXA5.
Sequence
C-DSHHGGKNSLSN
Host
Goat
Theoretical MW (kDa)
29.3
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:16000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — HOXA5
Entrez GeneID
3202Protein Accession#
NP_061975.2Gene Name
HOXA5
Gene Alias
HOX1, HOX1.3, HOX1C, MGC9376
Gene Description
homeobox A5
Omim ID
142952Gene Ontology
HyperlinkGene Summary
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis. [provided by RefSeq
Other Designations
homeo box 1C|homeo box A5|homeobox protein HOXA5
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Interactome
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Disease
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Publication Reference
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Leukaemic transformation by CALM-AF10 involves upregulation of Hoxa5 by hDOT1L.
Okada Y, Jiang Q, Lemieux M, Jeannotte L, Su L, Zhang Y.
Nature Cell Biology 2006 Sep; 8(9):1017.
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Leukaemic transformation by CALM-AF10 involves upregulation of Hoxa5 by hDOT1L.
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