TAZ polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
TAZ polyclonal antibody (Cat # PAB6881) (0.3 ug/mL) staining of human heart lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of TAZ.
Immunogen
A synthetic peptide corresponding to human TAZ.
Sequence
C-HLKTQAEQLHNH
Host
Goat
Theoretical MW (kDa)
33.5, 30.2, 31.7, 28
Reactivity
Human
Specificity
This antibody is expected to recognize isoforms 1to 4 (NP_000107.1; NP_851828.1; NP_851829.1; NP_851830.1, respectively).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
Western Blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
TAZ polyclonal antibody (Cat # PAB6881) (0.3 ug/mL) staining of human heart lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — TAZ
Entrez GeneID
6901Protein Accession#
NP_000107.1;NP_851828.1;NP_851829.1;NP_851830.1Gene Name
TAZ
Gene Alias
BTHS, CMD3A, EFE, EFE2, FLJ27390, G4.5, LVNCX, Taz1, XAP-2
Gene Description
tafazzin
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in this gene have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy (DCM), hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction (LVNC). Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is produced; the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound. Other alternatively spliced transcripts have been described but the full-length nature of all these transcripts is not known. [provided by RefSeq
Other Designations
OTTHUMP00000031946|OTTHUMP00000031947|OTTHUMP00000031948|OTTHUMP00000031949|OTTHUMP00000061673
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Interactome
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Disease
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Publication Reference
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Taz1, an outer mitochondrial membrane protein, affects stability and assembly of inner membrane protein complexes: implications for Barth Syndrome.
Brandner K, Mick DU, Frazier AE, Taylor RD, Meisinger C, Rehling P.
Molecular Biology of the Cell 2005 Nov; 16(11):5202.
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Taz1, an outer mitochondrial membrane protein, affects stability and assembly of inner membrane protein complexes: implications for Barth Syndrome.
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