CFC1 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
CFC1 polyclonal antibody (Cat # PAB6850, 2 ug/mL) staining of paraffin embedded mouse embryo liver. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of CFC1.
Immunogen
A synthetic peptide corresponding to human CFC1.
Sequence
HFTGRYCEHDQRRSEC
Host
Goat
Theoretical MW (kDa)
24.6
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
CFC1 polyclonal antibody (Cat # PAB6850, 2 ug/mL) staining of paraffin embedded mouse embryo liver. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CFC1
Entrez GeneID
55997Protein Accession#
NP_115934.1Gene Name
CFC1
Gene Alias
CRYPTIC, FLJ77897, HTX2, MGC133213
Gene Description
cripto, FRL-1, cryptic family 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the epidermal growth factor (EGF)- Cripto, Frl-1, and Cryptic (CFC) family. EGF-CFC family member proteins share a variant EGF-like motif, a conserved cysteine-rich domain, and a C-terminal hydrophobic region. These proteins play key roles in intercellular signaling pathways during vertebrate embryogenesis. Mutations in this gene can cause autosomal visceral heterotaxy. This protein is involved in left-right asymmetric morphogenesis during organ development. [provided by RefSeq
Other Designations
cryptic
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Interactome
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Disease
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Publication Reference
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Role of human cripto-1 in tumor angiogenesis.
Bianco C, Strizzi L, Ebert A, Chang C, Rehman A, Normanno N, Guedez L, Salloum R, Ginsburg E, Sun Y, Khan N, Hirota M, Wallace-Jones B, Wechselberger C, Vonderhaar BK, Tosato G, Stetler-Stevenson WG, Sanicola M, Salomon DS.
Journal of the National Cancer Institute 2005 Jan; 97(2):132.
Application：Func, Human, HUVECs, MCF-7 cells.
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Role of human cripto-1 in tumor angiogenesis.
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