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Last updated: 2014/10/20
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CFH polyclonal antibody

  • Catalog # : PAB6830
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of CFH.
  • Immunogen:
  • A synthetic peptide corresponding to human CFH.
  • Sequence:
  • C-HLVPDRKKDQYK
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 139
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize isoform a (NP_000177.2) only.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:32000)
    Western Blot (0.03-0.1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • CFH polyclonal antibody (Cat # PAB6830) staining (0.03 ug/mL) of human lung lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3075
  • Gene Name:
  • CFH
  • Gene Alias:
  • ARMD4,ARMS1,CFHL3,FH,FHL1,HF,HF1,HF2,HUS,MGC88246
  • Gene Description:
  • complement factor H
  • Gene Summary:
  • This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
  • Other Designations:
  • H factor 1 (complement),H factor 2 (complement),OTTHUMP00000033598,age-related maculopathy susceptibility 1,beta-1-H-globulin,beta-1H,complement factor H, isoform b,factor H,factor H-like 1
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