CCKBR polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of CCKBR.
Immunogen
A synthetic peptide corresponding to internal region of human CCKBR.
Sequence
C-FDGDSDSDSQSRVRNQ
Host
Goat
Theoretical MW (kDa)
48.4
Reactivity
Human, Rat
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:32000)
Western Blot (0.1-0.3 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-6 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunocytochemistry
Immunofluorescence
Enzyme-linked Immunoabsorbent Assay
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Gene Info — CCKBR
Entrez GeneID
887Protein Accession#
NP_795344.1Gene Name
CCKBR
Gene Alias
CCK-B, CCK2R, GASR
Gene Description
cholecystokinin B receptor
Omim ID
118445Gene Ontology
HyperlinkGene Summary
This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. [provided by RefSeq
Other Designations
CCK2 receptor|cholecystokinin-B receptor/gastrin receptor|gastrin receptor
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Interactome
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Pathway
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Disease
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Publication Reference
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Multifactorial diagnostic NIR imaging of CCK2R expressing tumors.
Kossatz S, Behe M, Mansi R, Saur D, Czerney P, Kaiser WA, Hilger I.
Biomaterials 2013 Jul; 34(21):5172.
Application:IHC-P, Human, Mouse, Mouse xenografts, A431 cells.
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Localization of cholecystokinin receptor subtypes in the endocine pancreas.
Morisset J, Julien S, Laine J.
The Journal of Histochemistry and Cytochemistry 2003 Nov; 51(11):1501.
Application:IHC-P, WB, Human, Rat, Brains, Islets.
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Multifactorial diagnostic NIR imaging of CCK2R expressing tumors.
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