ABCB9 polyclonal antibody
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More Files
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of ABCB9.
Immunogen
A synthetic peptide corresponding to human ABCB9.
Sequence
C-GHNEPVANGSHKA
Host
Goat
Theoretical MW (kDa)
79.8, 84.5
Reactivity
Human
Specificity
This antibody is expected to recognize both human isoforms of this protein (as represented by NP_062570 and NP_062571)
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:64000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (3-5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
ABCB9 polyclonal antibody (Cat # PAB6296, 3.8 ug/mL) staining of paraffin embedded human testis. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — ABCB9
Entrez GeneID
23457Protein Accession#
NP_062570;NP_062571Gene Name
ABCB9
Gene Alias
EST122234, KIAA1520, TAPL
Gene Description
ATP-binding cassette, sub-family B (MDR/TAP), member 9
Omim ID
605453Gene Ontology
HyperlinkGene Summary
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, this protein may play a role in lysosomes. Alternative splicing of this gene results in distinct isoforms which are likely to have different substrate specifications. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Publication Reference
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Characterization of ABCB9, an ATP binding cassette protein associated with lysosomes.
Zhang F, Zhang W, Liu L, Fisher CL, Hui D, Childs S, Dorovini-Zis K, Ling V.
The Journal of Biological Chemistry 2000 Jul; 275(30):23287.
Application:IHC-Fr, IF, WB-Tr, Human, Mouse, Rat, SKOV3 cells, Testis.
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Characterization of ABCB9, an ATP binding cassette protein associated with lysosomes.
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