TERF1 polyclonal antibody
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More Files
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Western Blot (Cell lysate)
TERF1 polyclonal antibody (Cat # PAB6118) staining (2 ug/mL) of HeLa lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 12 hour. Detected by western blot using chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of TERF1.
Immunogen
A synthetic peptide corresponding to human TERF1.
Sequence
C-TMKKLKLISSDSED
Host
Goat
Theoretical MW (kDa)
48.2, 50.2
Reactivity
Human
Specificity
This antibody is expected to recognize both human isoforms of this protein according to NP_003209.1 and NP_059523.1.
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:8000)
Western blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
TERF1 polyclonal antibody (Cat # PAB6118) staining (2 ug/mL) of HeLa lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 12 hour. Detected by western blot using chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — TERF1
Entrez GeneID
7013Protein Accession#
NP_003209.1;NP_059523.1Gene Name
TERF1
Gene Alias
FLJ41416, PIN2, TRBF1, TRF, TRF1, hTRF1-AS, t-TRF1
Gene Description
telomeric repeat binding factor (NIMA-interacting) 1
Omim ID
600951Gene Ontology
HyperlinkGene Summary
This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products. [provided by RefSeq
Other Designations
telomeric repeat binding factor 1|telomeric repeat binding protein 1
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Interactome
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Disease
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Publication Reference
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A human telomeric protein.
Chong L, van Steensel B, Broccoli D, Erdjument-Bromage H, Hanish J, Tempst P, de Lange T.
Science 1995 Dec; 270(5242):1663.
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A human telomeric protein.
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