GGPS1 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
The GGPS1 polyclonal antibody (Cat # PAB4325) is used in Western blot to detect GGPS1 in mouse cerebellum tissue lysate .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with GGPS1 polyclonal antibody (Cat # PAB4325) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining . This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of GGPS1.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human GGPS1.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Protein G purification
Recommend Usage
ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
The GGPS1 polyclonal antibody (Cat # PAB4325) is used in Western blot to detect GGPS1 in mouse cerebellum tissue lysate .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with GGPS1 polyclonal antibody (Cat # PAB4325) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining . This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated .Enzyme-linked Immunoabsorbent Assay
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Gene Info — GGPS1
Entrez GeneID
9453Protein Accession#
GGPP_HUMANGene Name
GGPS1
Gene Alias
GGPPS, GGPPS1
Gene Description
geranylgeranyl diphosphate synthase 1
Omim ID
606982Gene Ontology
HyperlinkGene Summary
This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
OTTHUMP00000036073
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Interactome
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Pathway
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Publication Reference
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Identification of the GGPS1 genes encoding geranylgeranyl diphosphate synthases from mouse and human.
Kainou T, Kawamura K, Tanaka K, Matsuda H, Kawamukai M.
Biochimica et Biophysica Acta 1999 Mar; 1437(3):333.
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Human geranylgeranyl diphosphate synthase. cDNA cloning and expression.
Kuzuguchi T, Morita Y, Sagami I, Sagami H, Ogura K.
The Journal of Biological Chemistry 1999 Feb; 274(9):5888.
Application：WB-Ti, Bovine, Brain.
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Human geranylgeranyl diphosphate synthase: isolation of the cDNA, chromosomal mapping and tissue expression.
Ericsson J, Greene JM, Carter KC, Shell BK, Duan DR, Florence C, Edwards PA.
Journal of Lipid Research 1998 Sep; 39(9):1731.
Application：WB-Ce, WB-Re, Human, HeLa cells, Recombinant protein.
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Identification of the GGPS1 genes encoding geranylgeranyl diphosphate synthases from mouse and human.
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