UBE2V1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of UBE2V1.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human UBE2V1.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Protein G purification
Recommend Usage
ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
The UBE2V1 polyclonal antibody (Cat # PAB4226) is used in Western blot to detect UBE2V1 in 293 cell lysate .Enzyme-linked Immunoabsorbent Assay
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Gene Info — UBE2V1
Entrez GeneID
7335Protein Accession#
NP_068823;Q9GZW1Gene Name
UBE2V1
Gene Alias
CIR1, CROC-1, CROC1, UBE2V, UEV-1, UEV1, UEV1A
Gene Description
ubiquitin-conjugating enzyme E2 variant 1
Omim ID
602995Gene Ontology
HyperlinkGene Summary
Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Multiple alternatively spliced transcripts encoding different isoforms have been described for this gene. A pseudogene has been identified which is also located on chromosome 20. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq
Other Designations
DNA-binding protein|OTTHUMP00000031795|OTTHUMP00000031796|OTTHUMP00000039980
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Interactome
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Publication Reference
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Fusion of the human gene for the polyubiquitination coeffector UEV1 with Kua, a newly identified gene.
Thomson TM, Lozano JJ, Loukili N, Carrio R, Serras F, Cormand B, Valeri M, Diaz VM, Abril J, Burset M, Merino J, Macaya A, Corominas M, Guigo R.
Genome Research 2000 Nov; 10(11):1743.
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Fusion of the human gene for the polyubiquitination coeffector UEV1 with Kua, a newly identified gene.
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